PPI Contraindications
What NOT To Do!

mom scratching head

PPI Contraindications. Important information of what NOT to do when giving any PPI medication to your infant with acid reflux. Your baby's safety is primary.

Contraindications means what you should NOT be giving your baby while you are giving your child any PPI medications.

Proton pump inhibitors are very safe and there is evidence that shows that there are little to no side affects. But like any medication, they are only safe if you use them properly.

We want your baby to get relief from infant acid reflux and keep them healthy and happy but we also want to keep your baby safe!

Food and PPI Contraindications

There are certain foods that you should try to avoid, at least for the first two hours of initial daily dosing.

  • High acidic fruits or juices
  • Foods that your baby may have an intolerance to (Milk, Soy, Corn, Protein)
  • Any allergen foods
  • Caffeine

We realize that you are aware of most of the food items that inflame your baby's acid reflux and we are well aware that you would not give your child any food products that they are allergic to. However, you may not be aware that the above food items could cause more severe acid reflux even after giving them a proton pump inhibitor. It's always better to have more information rather then less when it comes to PPI Contraindications.

PPI Contraindications with Chemicals or other Medications

Here we list any drugs or chemical products that you should not being giving while treating your baby with infant acid reflux.

Here we list any drugs or chemical products that you should not being giving while treating your baby with infant acid reflux.
  • H2 blockers:
    H2 blockers prevent PPI medications from working if they are taken too close together. A good rule to live by is "Do not give your baby any H2 blockers within four hours of giving them a PPI drug.
    Proton pump inhibitors work by inactivating the acid producing pumps in the parietal cells. This can only happen when the pumps are actively producing acid.
    H2 blockers prevent the pumps from producing acid so it's possible they can inhibit the full effectiveness of the PPI medication when they are given together. For more detailed information on H2 blockers, visit the H2 Blockers page.
  • Antacids:
    Antacids can dissolve the protective coating on PPIs. Antacids work much like the stomach acid in destroying the PPI medication before it reaches the small intestine. The site where PPI medications are absorbed and become effective. For more detailed information on Antacids, visit the Antacids page.
  • Sucralfate: Sulfated sucrose is a solution that is typically used as a secondary agent in treating acute ulceration of the stomach lining from excess acid production.
  • Beware of some acid containing medications such as some liquid Acetaninophen (the generic name for Liquid Tylenol®)

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