Proton Pump inhibitors can play an integral part in treating you baby's infant acid reflux and is just one of the many treatment options available to you and your baby. There are many PPIs to chose from and getting them compounded. Let's start with what they are, how they work and some product names.
The clinical description
of a PPI drug is a chemical compound (the technical name for medicine) that irreversibly inactivates the
pumps that produce stomach acid while the medication is in its effective
stage (the effective stage refers to the duration when the medicine starts and stops working).
To accurately describe a proton pump we need to describe the parietal cells that are located in the stomach. The function of the parietal cells are to secrete acid into the stomach to assist in breaking down what has been ingested (eaten). Proton pumps are part of this cell's membrane and that is the portion of the cell that pumps out the acid that the parietal cell secretes into the stomach.
PPI's work within the parietal cell's surface where acid is secreting. PPI's reach the location of the parietal cell secretion point through the blood stream. The PPIs react to the cell in a way that inactivates, both the pumps from secreting acid and in turn inactivates the parietal cells from producing acid.
The question is how do PPIs relate to infant acid reflux and are they safe to use and an infant acid reflux treatment? The answer is yes. PPI's are the safest, most effective medications available for treating acid reflux in both infants and children and the following have been approved by the FDA for pediatric use:
more in-depth information read the PPI Dosing Information Page This is very helpful in
understanding the Marci-kids dosing used by the
University of Missouri and Marcella Bothwell ENT and Jeffrey Phillips Pharm D. (Dr. P) in effectively treating
infant acid reflux.
Note: The doses recommended in the PPI information page and on the PPI dosing chart are not recommended by any proton pump inhibitor manufacturer or distribution company. These recommendations are representative of typical dosing used at Marci-kids website and have been proven to be effective in most cases.
Proton pump inhibitors should be used under the supervision of your doctor and all treatment options should be discussed with your medical team prior to use.
There are a number of proton pump inhibitor products on the market today.
Then they are further categorize as:
PPI's come in both OTC and Rx forms. Some examples are lansoprazole and ompeprazole.
This is a great time to pop over to that Acid & pH page and read about how acid and pH levels work, with interactive images that actually show you the process of digestion in a baby.
A proton pump inhibitor can be highly effective in controlling acid production. Additionally they have proven to be very safe and all of the PPIs on the market have very few, if any, side effects. Be sure to read about the contraindications (WHAT NOT TO DO OR USE WHEN USING A PROTON PUMP INHIBITOR) of using PPI's.